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Spermidine trihydrochloride

Name: Spermidine trihydrochloride
Brand: SIGMA

From microbial,synthetic, ≥99.0% (AT), nNos inhibitor, powder

Synonym(s):

N-(3-Aminopropyl)-1,4-butanediamine trihydrochloride

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About This Item

Linear Formula:

NH₂(CH₂)₃NH(CH₂)₄NH₂ · 3HCl

CAS Number:

334-50-9

Molecular Weight:

254.63

NACRES:

NA.77

PubChem Substance ID:

329769390

UNSPSC Code:

12352204

EC Number:

206-379-0

MDL number:

MFCD00012918

Beilstein/REAXYS Number:

3552356

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Properties

Product Name

Spermidine trihydrochloride, ≥99.0% (AT)

Quality Segment

200

biological source

microbial, synthetic

assay

≥99.0% (AT)

form

powder

mp

~250 °C (dec.), 257-259 °C (lit.)

solubility

H₂O: 0.1 g/mL, clear, colorless

storage temp.

room temp

SMILES string

Cl[H].Cl[H].Cl[H].NCCCCNCCCN

InChI

1S/C7H19N3.3ClH/c8-4-1-2-6-10-7-3-5-9;;;/h10H,1-9H2;3*1H

InChI key

LCNBIHVSOPXFMR-UHFFFAOYSA-N

Description

General description

Spermidine is a polyamine and a trivalent organic cation.

Application

Spermidine trihydrochloride has been used as standard for the detection of biogenic amines using HPLC.

Biochem/physiol Actions

Spermidine modulates various cellular activities like cellular development and differentiation, stability of DNA and apoptosis.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; Stimulates T₄ polynucleotide kinase activity.

Inhibits neuronal nitric oxide synthase (nNOS). Binds and precipitates DNA; may be used for purification of DNA binding proteins. Stimulates T₄ polynucleotide kinase activity.

Disclaimer

Solutions should be sterile-filtered, not autoclaved, if sterile solution is necessary. Spermidine deaminates with time; solutions should be stored frozen. Prepare new solutions frequently.

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This Item	85578	56766-M	S2501
SAFC 85580 Spermidine trihydrochloride	Sigma-Aldrich 85578 Spermidine trihydrochloride	Sigma-Aldrich 56766-M Spermidine, Trihydrochloride	Sigma-Aldrich S2501 Spermidine trihydrochloride
assay ≥99.0% (AT)	assay ≥99.0% (TLC), ≥99.5% (AT)	assay ≥98% (TLC)	assay ≥98% (TLC)
biological source microbial, synthetic	biological source -	biological source -	biological source microbial, synthetic
Quality Level 200	Quality Level 100	Quality Level 100	Quality Level 200
form powder	form powder	form solid	form powder
storage temp. room temp	storage temp. -	storage temp. 10-30°C	storage temp. room temp
solubility H₂O: 0.1 g/mL, clear, colorless	solubility H₂O: 1 M at 20 °C, clear, colorless	solubility ethanol: soluble, water: soluble	solubility water: 100 mg/mL, clear, colorless

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pictograms

GHS07

signalword

Warning

hcodes

H315,H319

pcodes

P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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