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Y0000063

Heptaminol hydrochloride

European Pharmacopoeia (EP) Reference Standard

Synonym(s):

6-Amino-2-methyl-2-heptanol hydrochloride, Heptaminol hydrochloride

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About This Item

Linear Formula:
CH3CH(NH2)(CH2)3C(OH)(CH3)2 · HCl
CAS Number:
Molecular Weight:
181.70
Beilstein:
3673011
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

heptaminol

manufacturer/tradename

EDQM

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl.CC(N)CCCC(C)(C)O

InChI

1S/C8H19NO.ClH/c1-7(9)5-4-6-8(2,3)10;/h7,10H,4-6,9H2,1-3H3;1H

InChI key

JZNBMCOSOXIZJB-UHFFFAOYSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Heptaminol hydrochloride EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Packaging

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Other Notes

Sales restrictions may apply.

related product

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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D Milon et al.
Fundamental & clinical pharmacology, 4(6), 695-705 (1990-01-01)
Heptaminol is a molecule with experimental cardiovascular analeptic properties. In this double-blind vs placebo trial, the potency, so far unproven, of the injectable form of a 626 mg dose of heptaminol chlorhydrate on spontaneous or induced orthostatic hypotension (OH), was
[A comparison of various phlebotonic agents on human endothelial cells of veins subjected to hypoxia].
J Remacle et al.
Phlebologie, 44(4), 881-889 (1991-11-01)
P D Drumheller et al.
Arteriosclerosis and thrombosis : a journal of vascular biology, 11(5), 1258-1265 (1991-09-01)
An endothelial cell monolayer with a single mechanically lysed cell was used as a model to examine the extent, kinetics, and nature of local calcium mobilization in the neighborhood of a wound. Individual endothelial cells from confluent monolayers were mechanically
N Peineau et al.
British journal of pharmacology, 107(1), 104-108 (1992-09-01)
1. The effects of heptaminol on calcium current amplitude and characteristics were studied in single ventricular myocytes of guinea-pig by use of the whole cell configuration of the patch clamp technique. 2. A concentration-dependent decrease in ICa amplitude was observed.
W Regina et al.
L'Encephale, 25(3), 252-258 (1999-08-06)
Milnacipran is a new antidepressant which has been developed for its selective inhibition of both serotonin and noradrenaline reuptake with a good safety and tolerability profile. The efficacy and tolerance profile of this antidepressant have been compared with those of

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