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D116408

Sigma-Aldrich

2,7-Dihydroxynaphthalene

97%

Synonym(s):

2,7-Naphthalenediol

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About This Item

Linear Formula:
C10H6(OH)2
CAS Number:
Molecular Weight:
160.17
Beilstein:
2042383
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

powder

mp

185-190 °C (lit.)

SMILES string

Oc1ccc2ccc(O)cc2c1

InChI

1S/C10H8O2/c11-9-3-1-7-2-4-10(12)6-8(7)5-9/h1-6,11-12H

InChI key

DFQICHCWIIJABH-UHFFFAOYSA-N

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General description

2,7-Dihydroxynaphthalene is a organic building block used to prepare sulfonic acids, divinylnaphthalenes, dyes, pigments, and fluorescent whiteners.

Application

Starting material for the synthesis of sulfonic acids and divinylnaphthalenes.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Allergic contact dermatitis from 2,7-dihydroxynaphthalene in hair dye.
A Eskelinen et al.
Contact dermatitis, 36(6), 312-313 (1997-06-01)
Alexandru Chichirau et al.
Free radical biology & medicine, 38(3), 344-355 (2005-01-05)
ortho-Hydroxyphenols (catechols) form a common structural unit in naturally occurring antioxidants such as polyphenols. They also show pro-oxidant characteristics which depend on their particular structure. Here we examined the acetylated versions of three catechols and a naphthalenediol for cytotoxicity to
Efficient lactic acid-catalyzed route to naphthopyranopyrimidines under solvent-free conditions
Sadeh FN, et al.
Organic preparations and procedures international, 49, 35-44 (2017)
G J Kemperman et al.
Organic letters, 2(18), 2829-2831 (2000-08-31)
[structure: see text] The cephalosporin antibiotic Cefadroxil can be epimerized at the alpha-carbon of its amino acid side chain using pyridoxal as the mediator. By clathration with 2,7-dihydroxynaphthalene, the desired diastereomer can be selectively withdrawn from the equilibrating mixture of
Maria Bonaccio et al.
Biochemistry, 44(21), 7656-7668 (2005-05-25)
The insulin hexamer is an allosteric protein widely used in formulations for the treatment of diabetes. The hexamer exhibits positive and negative cooperativity and apparent half-site binding activity, reflecting the interconversion of three allosteric states, designated as T6, T3R3, and

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