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909149

Sigma-Aldrich

Poly(ethylene glycol) diamine

average Mn 400

Synonym(s):

Poly(ethylene glycol) bis(amine), Polyethylene glycol, O,O′-Bis(2-aminoethyl)polyethylene glycol, Diaminopolyethylene glycol, PEG-diamine, Polyoxyethylene bis(amine)

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About This Item

Linear Formula:
H2N(CH2CH2O)nCH2CH2NH2
CAS Number:
24991-53-5
MDL number:
MFCD00132004
UNSPSC Code:
43211915
NACRES:
NA.23

form

viscous liquid

mol wt

average Mn 400 (by NMR)
average Mn 400

reaction suitability

reagent type: cross-linking reagent
reactivity: carboxyl reactive

color

colorless to pale yellow

Ω-end

amine

α-end

amine

polymer architecture

shape: linear
functionality: homobifunctional

storage temp.

2-8°C

InChI

1S/C6H16N2O2/c7-1-3-9-5-6-10-4-2-8/h1-8H2

InChI key

IWBOPFCKHIJFMS-UHFFFAOYSA-N

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Application

PEGylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of PEG improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. Polymer for preparing enzyme conjugates soluble in organic solvents; promising drug carrier.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
MKCT0872
MKCS2410
MKCL5203

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Attaching folic acid on gold nanoparticles using noncovalent interaction via different polyethylene glycol backbones and targeting of cancer cells.
Bhattacharya R, et al.
Nanomedicine: Nanotechnology, Biology, and Medicine, 3, 224-238 (2007)
Facile Synthesis of a Degradable Poly(ethylene glycol) Platform with Tunable Acid Sensitivity at Physiologically Relevant pH.
Li Z C, et al.
Macromolecules, 51, 6571-6579 (2018)
Rigidity of Two-Component Hydrogels Prepared from Alginate and Poly(ethylene glycol)-Diamines.
Eiselt P, et al.
Macromolecules, 32 (17), 5561-5566 (1999)

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