Skip to Content
Merck
All Photos(2)

Documents

900912

Sigma-Aldrich

Biotin picolyl azide

Synonym(s):

Biotin-functionalized Picolyl Azide

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C27H42N8O7S
Molecular Weight:
622.74
UNSPSC Code:
12352125
NACRES:
NA.22

form

powder or crystals

Quality Level

100

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

Application

Biotin picolyl azide is a linker with an azide group for attachment to alkynes, a biotin for capture by streptavidin, and a picolyl group for faster azide reactivity. The picolyl azide chelates Cu(I) to enhance the reactivity of the azide-alkyne cycloaddition. This is an advantage especially when working with low concentrations of alkynes and can also enable reduction of the copper concentration.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

related product

Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

A highly sensitive protocol for microscopy of alkyne lipids and fluorescently tagged or immunostained proteins.
Gaebler A, et al.
Journal of Lipid Research, 57(10), 1934-1947 (2016)
Spontaneous and specific chemical cross-linking in live cells to capture and identify protein interactions.
Yang B, et al.
Nature Communications, 8(1), 2240-2240 (2017)
Lydia Boike et al.
Cell chemical biology, 28(1), 4-13 (2020-09-24)
MYC is a major oncogenic transcriptional driver of most human cancers that has remained intractable to direct targeting because much of MYC is intrinsically disordered. Here, we have performed a cysteine-reactive covalent ligand screen to identify compounds that could disrupt

Articles

Crosslinkers Selection Guide

Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.

Crosslinkers Selection Guide

Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.

Crosslinkers Selection Guide

Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.

Crosslinkers Selection Guide

Choosing the right crosslinker for your biochemical or bioconjugation research can be challenging. Our selection guide can help you find the perfect match for your applications.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service