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525286

Sigma-Aldrich

Sucrose acetate isobutyrate solution

90 wt. % in denatured ethanol

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About This Item

Empirical Formula (Hill Notation):
C40H62O19
CAS Number:
Molecular Weight:
846.91
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.22

vapor pressure

40 mmHg ( 20 °C)

Quality Level

concentration

90 wt. % in denatured ethanol

bp

105 °C

density

1.1 g/mL at 25 °C

SMILES string

CC(C)C(=O)OC[C@]1(O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@@H]1OC(=O)C(C)C)O[C@H]2O[C@H](COC(C)=O)[C@@H](OC(=O)C(C)C)[C@H](OC(=O)C(C)C)[C@H]2OC(=O)C(C)C

InChI

1S/C40H62O19/c1-18(2)33(43)51-17-40(32(57-38(48)23(11)12)29(54-35(45)20(5)6)27(58-40)16-50-25(14)42)59-39-31(56-37(47)22(9)10)30(55-36(46)21(7)8)28(53-34(44)19(3)4)26(52-39)15-49-24(13)41/h18-23,26-32,39H,15-17H2,1-14H3/t26-,27-,28-,29-,30+,31-,32+,39-,40+/m1/s1

InChI key

ZNEBZIJCDDCNRC-SWTLDUCYSA-N

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Pictograms

Flame

Signal Word

Danger

Hazard Statements

Hazard Classifications

Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

60.6 °F - closed cup

Flash Point(C)

15.9 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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K M Mackenzie et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 36(2), 111-120 (1998-03-31)
Sucrose acetate isobutyrate (SAIB), a food additive used as a flavour emulsion stabilizer in citrus-based soft drinks, was evaluated for chronic toxicity in B6C3F1 mice and Fischer 344 rats. SAIB dissolved in acetone was blended into NIH07 rodent diet at
James Lee et al.
Toxicology and applied pharmacology, 215(1), 64-70 (2006-04-25)
Sucrose acetate isobutyrate (SAIB) is a water insoluble, biodegradable gel used for controlled-release oral and subcutaneous drug delivery. We investigated SAIB compatibility in the rat central nervous system (CNS) by implanting solutions of SAIB in adult and in neonatal brains.
Yaxin Lu et al.
Journal of pharmaceutical sciences, 96(12), 3252-3262 (2007-08-28)
The objective of this study was to develop sustained-release sucrose acetate isobutyrate (SAIB) in situ formulations of risperidone for parenteral delivery. The formulations contained SAIB, solvent (anhydrous ethanol, ethyl lactate, or N-methyl-2-pyrrolidone), and additives such as polylactic acid (PLA). In
Franklin W Okumu et al.
Biomaterials, 23(22), 4353-4358 (2002-09-11)
The purpose of this study was to evaluate the release of recombinant human growth hormone (rhGH) from a novel non-polymeric sustained release system, SABER. The SABER system consists of sucrose acetate isobutryate, a solvent and a polymeric release modifier. Spray
Dilek Sendil Keskin et al.
Biomaterials, 26(18), 4023-4034 (2005-01-01)
Bone morphogenetic proteins (BMPs) are osteoinductive proteins used intensively in clinical investigations involving various bone-related treatments. Owing to their high potential in new bone formation they require local application at the treatment site. For this purpose various controlled delivery systems

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