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Key Documents

X6250

Sigma-Aldrich

Xanthophyll

from marigold

Synonym(s):

α-Carotene-3,3′-diol, β, ε-carotene, β, ε-carotene-3,3′-diol, Lutein

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€226.00
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€889.00

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1 MG
€226.00
5 MG
€889.00

About This Item

Empirical Formula (Hill Notation):
C40H56O2
CAS Number:
Molecular Weight:
568.87
Beilstein:
2068547
EC Number:
MDL number:
UNSPSC Code:
12352205
PubChem Substance ID:
NACRES:
NA.79

€226.00


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biological source

marigold

Quality Level

form

powder

color

orange to brown

shipped in

dry ice

storage temp.

−70°C

SMILES string

CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)C[C@@H](O)CC1(C)C)\C=C\C=C(C)\C=C\[C@H]2C(C)=C[C@H](O)CC2(C)C

InChI

1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1

InChI key

KBPHJBAIARWVSC-RGZFRNHPSA-N

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General description

Xanthophylls are oxygenated derivatives of carotenoids. It consists of oxygen atoms.[1] Xanthophylls are yellow pigments and are found majorly in the leaves of most green plants.[2]

Application

Xanthophyll has been used:
  • to quantify circulating lutein in birds[3]
  • to study its effect on the synthesis of factor D (FD) by adipocytes[4]
  • for the quantification of carotenoids from the leaves of Brassica oleracea[5]

Biochem/physiol Actions

Dietary carotenoid with no vitamin A potency. Increases macular pigment concentration in the eye and may improve visual function.
Xanthophyll/Lutein functions as an accessory light-harvesting pigment. It also acts as quenchers of singlet oxygen and chlorophyll triplet states to exhibit protection against photooxidative damage. Xanthophyll is involved in photosynthesis. It has antioxidant properties.[1]

Packaging

Dry powder packed under Argon.

Quality

Minimum 70% total carotenoids as xanthophyll.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Extraction and purification of carotenoids from vegetables
Rebecca LJ, et al.
Journal of Chemical and Pharmaceutical Research, 6(4), 594-598 (2014)
Carotenoids, birdsong and oxidative status: administration of dietary lutein is associated with an increase in song rate and circulating antioxidants (albumin and cholesterol) and a decrease in oxidative damage
Casagrande S, et al.
PLoS ONE, 9(12), e115899-e115899 (2014)
Effect of green juice and their bioactive compounds on genotoxicity induced by alkylating agents in mice
Fagundes GE, et al.
Journal of Toxicology and Environmental Health. Part A, 80(13-15), 756-766 (2017)
Jueun Oh et al.
Mediators of inflammation, 2013, 787042-787042 (2013-03-28)
Lutein is a naturally occurring carotenoid with antioxidative, antitumorigenic, antiangiogenic, photoprotective, hepatoprotective, and neuroprotective properties. Although the anti-inflammatory effects of lutein have previously been described, the mechanism of its anti-inflammatory action has not been fully elucidated. Therefore, in the present
Ian J Murray et al.
Investigative ophthalmology & visual science, 54(3), 1781-1788 (2013-02-07)
We investigated the effect of daily supplementation with lutein (L) capsules on macular pigment optical density (MPOD) and visual acuity (VA) in patients with early age-related macular degeneration (AMD). A randomized, double-blind, placebo-controlled, two-center investigation of the effects of L

Articles

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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