Aquaporin 1 (AQP1) is expressed in the nervous system. The gene ID of the protein is 25240.
Specificity
Detects ~28.5 kDa. May detect larger glycosylated bands ~35-50 kDa.
Immunogen
N-terminal peptide
Biochem/physiol Actions
Aquaporin 1 (AQP1) aids in transporting water across cell membranes. It also contributes to the migration and proliferation of pulmonary arterial smooth muscle cells.
Features and Benefits
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Physical form
PBS, pH 7..4, 50% glycerol, and 0.09% sodium azide
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Aquaporin 1 (AQP1) is a member of a family of small, integral membrane water-transporting proteins, which facilitate water movement across cell membranes in response to osmotic gradients. Several papers have studied the expression and function of the AQPs in the
American journal of respiratory cell and molecular biology, 50(6), 1010-1020 (2013-12-18)
Pulmonary arterial smooth muscle cell (PASMC) proliferation and migration are important contributors to the vascular remodeling that occurs during development of pulmonary hypertension. We previously demonstrated that aquaporin (AQP)1, a member of the water channel family of proteins, was expressed
Cancer cell toxicity to therapeutic H2O2 varies widely depending on cell type. Interestingly, it has been observed that different cancer cell types have varying peroxiporin expression. We hypothesize that variation in peroxiporin expression can alter cell susceptibility to therapeutic H2O2
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