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RAB0648

Sigma-Aldrich

Human D-Dimer ELISA Kit

for serum, plasma, cell culture supernatants and urine

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.84
Pricing and availability is not currently available. Contact Technical Service

species reactivity

human

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

input

sample type serum
sample type urine
sample type plasma
sample type cell culture supernatant(s)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.08 pg/mL
standard curve range: 0.082-60 pg/mL

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... FGA(2243)

General description

This ELISA kit provides for the quantitative measurement of human D-Dimer in cell culture supernatants, plasma and serum.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

D-Dimer is a fibrin degradation product. It facilitates the activation of the coagulation system.[1] Overexpression of the D-dimer contributes to endothelial dysfunction in virologically suppressed, human immunodeficiency virus (HIV) -infected adults.[1] In addition, increased expression of the gene also serves as a potent predictive biomarker, in patients at risk for disseminated intravascular coagulation (DIC).[2]

Other Notes

A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.

Kit Components Also Available Separately

Product No.
Description
SDS
  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS
  • RABSTOP3ELISA Stop Solution (Item I)SDS
  • RABELADEELISA 5X Assay/Sample Diluent Buffer E (Item E2)SDS
  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion
GHS05

Signal Word

Warning

Hazard Statements

H290

Precautionary Statements

P234 - P390

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
0810J0020
0117J0020
0920I0020
0830I0020
0722I0020

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Diagnosis of disseminated intravascular coagulation. Role of D-dimer.
Carr JM, et al.
American Journal of Clinical Pathology, 91(3), 280-287 (1989)
Elevated D-dimer is independently associated with endothelial dysfunction: a cross-sectional study in HIV-infected adults on antiretroviral therapy
Hileman CO, et al.
Antiviral Ther., 17(7), 1345-1345 (2012)

Questions

1–2 of 2 Questions  

  1. RAB0648 Sigma-Aldrich Human D-Dimer ELISA Kit Does this cross-react with monkey (cyno/NHP)?

    1 answer

    1. This kit has not been tested for suitability in monkey. It is recommended that the end user run a protein BLAST to compare homology between species. For ELISA, if there is a >60% homology, it is likely the kit can work for NHP samples.

      Helpful?

  2. What anticoagulants can be used to collect plasma samples for the Human D-Dimer ELISA (RAB0648)?

    1 answer

    1. The Human D-Dimer ELISA (RAB0648) has been validated with plasma samples treated with EDTA, Citrate, and Sodium heparin.

      Helpful?

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