G5894
Glutaminase from Escherichia coli
Grade VII, lyophilized powder, 500-1,500 units/mg protein
Synonym(s):
L-Glutamine amidohydrolase
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About This Item
CAS Number:
MDL number:
UNSPSC Code:
12352204
NACRES:
NA.54
Recommended Products
type
Grade VII
Quality Level
form
lyophilized powder
specific activity
500-1,500 units/mg protein
composition
Protein, ~10% Lowry
storage temp.
−20°C
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Biochem/physiol Actions
Glutaminase catalyzes the conversion of glutamine to glutamate.
Linkage
Chromatographically purified from Grade V
Unit Definition
One unit will deaminate 1.0 μmole of L-glutamine per min at pH 4.9 at 37 °C.
Physical form
Lyophilized powder containing stabilizer and potassium succinate
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
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Felix List et al.
Chemistry & biology, 19(12), 1589-1599 (2012-12-25)
Nitrogen is incorporated into various metabolites by multifunctional glutamine amidotransferases via reactive ammonia generated by glutaminase hydrolysis of glutamine. Although this process is generally tightly regulated by subsequent synthase activity, little is known about how the glutaminase is inhibited in
N V Zharkova et al.
Biomeditsinskaia khimiia, 58(2), 220-223 (2012-06-26)
Acute alcohol intoxication in rats with alloxan diabetes is accompanied by the increase of urea and uric acid and by the decrease in free fatty acids in serum. In the liver of experimental animals the increase of activity of glutamate
Catherine Qiurong Pan et al.
FEBS letters, 586(17), 2674-2691 (2012-06-20)
The BNIP-2 and Cdc42GAP Homology (BCH) domains constitute a new and expanding family of highly conserved scaffold protein domains that regulate Rho, Ras and MAPK signaling, leading to cell growth, apoptosis, morphogenesis, migration and differentiation. Such versatility is achieved via
Eva M J Peters et al.
The Journal of investigative dermatology, 133(5), 1150-1160 (2012-12-14)
Determining hitherto uninvestigated and safe targets to halt the aging process is important in our aging society. Graying is a hallmark of the aging process and may be used to identify aging tissue for comparative analysis. Here we analyzed differential
Javier Ampuero et al.
PloS one, 7(11), e49279-e49279 (2012-11-21)
To investigate the influence of metformin use on liver dysfunction and hepatic encephalopathy in a retrospective cohort of diabetic cirrhotic patients. To analyze the impact of metformin on glutaminase activity and ammonia production in vitro. Eighty-two cirrhotic patients with type
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