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MAB5540

Sigma-Aldrich

Anti-Olig1 Antibody

ascites fluid, Chemicon®

Synonym(s):

Oligo1, Oligodendrocyte transcription factor 1

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

antibody form

ascites fluid

antibody product type

primary antibodies

clone

monoclonal

species reactivity

human, mouse, rat

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG2b

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... OLIG1(116448)
rat ... Olig1(60394)

General description

Olig-1 is a bHLH transcription factor that is expressed by oligodendrocytes in the brain where it promotes oligodendrocyte formation and maturation. Olig1 cooperates with Olig2 to establish the pMN domain of the embryonic neural tube.

Specificity

Oligodendrocyte marker Olig1. The antibody typically stains cell in either the cytoplasm or nucleus depending on cell type. Staining will be present in the nucleus of remyelinating oligodendrocytes.

Immunogen

Fusion protein from mouse Olig1.

Application

Anti-Olig1 Antibody is an antibody against Olig1 for use in WB, IC, IH.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Physical form

Liquid ascites fluid.

Storage and Stability

Maintain at -20degC in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

Analysis Note

Control
Positive control: Corpus callosium Negative control: skin or non-neural organs

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Mario Marotta et al.
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Elena K Fetisova et al.
Oxidative medicine and cellular longevity, 2019, 2082561-2082561 (2019-07-30)
Multiple sclerosis (MS) is a heterogeneous autoimmune disease of unknown etiology characterized by inflammation, demyelination, and axonal degeneration that affects both the white and gray matter of CNS. Recent large-scale epidemiological and genomic studies identified several genetic and environmental risk
Jenna J Boulanger et al.
Frontiers in neuroscience, 11, 143-143 (2017-04-13)
Key Points Oligodendrocyte precursor cells express doublecortin, a microtubule-associated protein.Oligodendrocyte precursor cells express doublecortin, but at a lower level of expression than in neuronal precursor.Doublecortin is not associated with a potential immature neuronal phenotype in Oligodendrocyte precursor cells. Oligodendrocyte precursor
Julia C Terek et al.
ACS pharmacology & translational science, 6(2), 320-333 (2023-02-18)
Biomaterials derived from brain extracellular matrix (ECM) have the potential to promote neural tissue regeneration by providing instructive cues that can direct cell survival, proliferation, and differentiation. This study focused on the development and characterization of microcarriers derived from decellularized
Xue Fang et al.
Neuroscience bulletin, 33(6), 603-615 (2017-07-19)
Multiple sclerosis (MS) is a classical inflammatory demyelinating disease of the central nervous system (CNS). Microglia are the main resident immune cells in the CNS and are closely associated with the pathogenesis of MS. In the present study, we found

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