Synthetic peptide from the EL2 region of human dopamine transporter.
Application
Anti-Dopamine Transporter Antibody, extracellular Loop 2 is an antibody against Dopamine Transporter for use in IH & WB.
Immunoblotting: 1:500-1:1,000
Immunohistochemistry using formaldehyde-fixed brain sections: 1:500-1:1,000
Optimal working dilutions must be determined by the end user.
Research Category Neuroscience
Research Sub Category Ion Channels & Transporters
Physical form
Affinity purified immunoglobulin. Each vial contains ~33 μg of affinity-purified antibody in 100 μL of 10 mM HEPES (pH 7.5), 150 mM NaCl with 100 μg/mL BSA and 50% glycerol.
Storage and Stability
Maintain at -20 to -80°C in undiluted aliquots for up to six months. Store in a NON-self-defrosting freezer. Avoid repeated freeze-thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Certificates of Analysis (COA)
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Parkinson's disease (PD) is marked by a loss of dopamine neurons, decreased dopamine transporter (DAT) and tyrosine hydroxylase (TH) expression. However, this validation approach cannot be used for diagnostic, drug effectiveness or investigational purposes in human patients because midbrain tissue
Frontiers in cellular neuroscience, 13, 35-35 (2019-03-05)
The dopamine transporter (DAT) is a plasma membrane protein responsible for the uptake of released dopamine back to the presynaptic terminal and ending dopamine neurotransmission. The DAT is the molecular target for cocaine and amphetamine as well as a number
Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3.
Pathophysiological damages and loss of function of dopamine neurons precede their demise and contribute to the early phases of Parkinson's disease. The presence of aberrant intracellular pathological inclusions of the protein α-synuclein within ventral midbrain dopaminergic neurons is one of
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