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Key Documents

AB1128

Sigma-Aldrich

Anti-Respiratory Syncytial Virus Antibody

Chemicon®, from goat

Synonym(s):

RSV

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

goat

Quality Level

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)

shipped in

wet ice

Specificity

Recognizes RSV, all antigens. Does not react with Para 1-3, Influenza A & B and Adenovirus by IFA. Non reactive with HEp-2 cells and WI-38 cells.

Immunogen

Human RSV isolate

Application

Anti-Respiratory Syncytial Virus Antibody is an antibody against Respiratory Syncytial Virus for use in ELISA, IF, IH(P).
Indirect immunofluorescence: 1:480.

Reactive in paraffin embedded sections (see matsuse, et al 2000).

ELISA: 1:10,000

Fusion inhibition (1:256)

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Purified immunoglobulin in PBS (0.01 M, pH 7.2) with 0.1% sodium azide.

Storage and Stability

Maintain -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Respiratory syncytial virus (RSV) suppression of glucocorticoid receptor phosphorylation does not account for repression of transactivation.
Webster Marketon, JI; Corry, J
FEBS Open Bio null
Nanobodies? specific for respiratory syncytial virus fusion protein protect against infection by inhibition of fusion.
Schepens, B; Iba?ez, LI; De Baets, S; Hultberg, A; Bogaert, P; De Bleser, P; Vervalle et al.
The Journal of Infectious Diseases null
Protein kinase C-alpha activity is required for respiratory syncytial virus fusion to human bronchial epithelial cells.
San-Juan-Vergara, H; Peeples, ME; Lockey, RF; Mohapatra, SS
Journal of virology null
Recurrent respiratory syncytial virus infections in allergen-sensitized mice lead to persistent airway inflammation and hyperresponsiveness.
H Matsuse, A K Behera, M Kumar, H Rabb, R F Lockey, S S Mohapatra
Journal of immunology (Baltimore, Md. : 1950) (1950)
Weidong Zhang et al.
Nature medicine, 11(1), 56-62 (2004-12-28)
Respiratory syncytial virus (RSV) infection is one of the major causes of respiratory tract infection for which no vaccine or antiviral treatment is available. The RSV NS1 protein seems to antagonize the host interferon (IFN) response; however, its mechanism is

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