PEAK1 belongs to the protein kinase superfamily. PEAK1 is also called Tyrosine-protein kinase SgK269 and Sugen kinase 269. It contains a divergent and possibly inactive eukaryotic protein kinase domain. It has one human paralog, known as SgK223 or pragmin. These two constitute the NKF3 subfamily of protein kinases, found in vertebrates and echinoderms.
Specificity
Other species have not been tested.
Immunogen
Epitope: 1511-1660 aa
Recombinant Protein, aa: 1511-1660. Homology: 100% human and chimp; 96% pig and horse; 90% mouse; 88% rat
Application
This Anti-PEAK1 Antibody is validated for use in WB for the detection of PEAK1.
Quality
Routinely evaluated by Western Blot on FG Nonstim /Nonstrvd lysate.
Target description
250 kDa
Analysis Note
Control FG Nonstim /Nonstrvd lysate
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
There remains intense interest in tractable approaches to target or silence the KRAS oncoprotein as a rational therapeutic strategy to attack pancreatic ductal adenocarcinoma (PDAC) and other cancers that overexpress it. Here we provide evidence that accumulation of the KRAS
Collagen signaling enhances tumor progression after anti-VEGF therapy in a murine model of pancreatic ductal adenocarcinoma.
Molecular cancer therapeutics, 16(11), 2473-2485 (2017-09-03)
The extracellular matrix (ECM), a principal component of pancreatic ductal adenocarcinoma (PDA), is rich in fibrillar collagens that facilitate tumor cell survival and chemoresistance. Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that specifically binds fibrillar collagens and
Questions
Reviews
★★★★★ No rating value
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
