05-730
Anti-STEP Antibody, clone 23E5
clone 23E5, Upstate®, from mouse
Synonym(s):
Neural-specific protein-tyrosine phosphatase, PTPN5
Sign Into View Organizational & Contract Pricing
Select a Size
100 μG
€598.00
All Photos(1)
Select a Size
Change View
100 μG
€598.00
About This Item
UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Recommended Products
biological source
mouse
Quality Level
antibody form
purified antibody
antibody product type
primary antibodies
clone
23E5, monoclonal
species reactivity
mouse, rat, human
manufacturer/tradename
Upstate®
technique(s)
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
isotype
IgG
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Gene Information
human ... PTPN5(84867)
Specificity
STEP61, STEP46, STEP38 and STEP20
Immunogen
Peptide corresponding to amino acids 57-74 of rat STEP46
Application
Anti-STEP Antibody, clone 23E5 is an antibody against STEP for use in IP, WB, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Ion Channels & Transporters
Neurodegenerative Diseases
Ion Channels & Transporters
Neurodegenerative Diseases
Quality
routinely evaluated by immunoblot on in RIPA lysates from whole rat brain preparations
Target description
~64-66 (doublet) & 46
Physical form
0.1M Tris-glycine, pH 7.4, 0.15M NaCl, 0.05% sodium azide before the addition of glycerol to 30%
Format: Purified
Protein G Purified
Storage and Stability
2 years at -20°C
Legal Information
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Not finding the right product?
Try our Product Selector Tool.
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Jun Chen et al.
The European journal of neuroscience, 29(2), 287-306 (2009-02-10)
Although the mechanisms underlying striatal neurodegeneration are poorly understood, we have shown that striatal pathogenesis may be initiated by high synaptic levels of extracellular dopamine (DA). Here we investigated in rat striatal primary neurons the mobilization of the mitogen-activated protein
A protein tyrosine phosphatase expressed within dopaminoceptive neurons of the basal ganglia and related structures.
Lombroso, P J, et al.
The Journal of Neuroscience, 13, 3064-3074 (1993)
Daniel Radzicki et al.
Hippocampus, 33(3), 133-149 (2023-02-11)
Hippocampal area CA2 is a molecularly and functionally distinct region of the hippocampus that has classically been defined as the area with large pyramidal neurons lacking input from the dentate gyrus and the thorny excrescences (TEs) characteristic of CA3 neurons.
Serena M Dudek et al.
Hippocampus, 33(6), 700-711 (2023-05-09)
Since 1959, the Russian Farm-Fox study has bred foxes to be either tame or, more recently, aggressive, and scientists have used them to gain insight into the brain structures associated with these behavioral features. In mice, hippocampal area CA2 has
Sofía Espinoza et al.
BMC biology, 18(1), 164-164 (2020-11-08)
Cognitive dysfunction (CD) is common among patients with the autoimmune disease systemic lupus erythematosus (SLE). Anti-ribosomal P autoantibodies associate with this dysfunction and have neuropathogenic effects that are mediated by cross-reacting with neuronal surface P antigen (NSPA) protein. Elucidating the
Active Filters
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service
