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A-046

Supelco

Atropine solution

1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

Atropine solution

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About This Item

Empirical Formula (Hill Notation):
C17H23NO3
CAS Number:
Molecular Weight:
289.37
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

form

liquid

feature

SNAP-N-SPIKE®. SNAP-N-SHOOT®

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

1.0 mg/mL in acetonitrile

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

application(s)

clinical testing

format

single component solution

storage temp.

−20°C

InChI

1S/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3

InChI key

RKUNBYITZUJHSG-UHFFFAOYSA-N

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General description

A Certified Spiking Solution® suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications from clinical toxicology to forensic analysis and pharmaceutical research. Atropine is a pharmaceutical drug used for treatment of cardiac conditions.

For the analysis of the phytotoxins. Tropane alkaloid.

Application


  • Atropine sulfate solution: Study conducted a systematic review and meta-analysis on the effectiveness of atropine in managing sialorrhea, highlighting its use as a muscarinic antagonist reagent in clinical settings, providing critical insights for pharmacological research atropine applications (Yellepeddi et al., 2024).

  • Pharmacological research atropine: The clinical pharmacokinetics of an atropine oral gel formulation were studied in healthy volunteers, underscoring its importance in acetylcholine receptor studies and its application in developing pharmacokinetic profiles for pharmaceutical research (Parrot et al., 2024).

  • Atropine as a muscarinic antagonist in pharmacological research: The study discussed the utility of plant alkaloids, including atropine, in treating eye diseases, illustrating atropine′s role as a vital ophthalmic research chemical and its broader implications in medical research (Lorrai et al., 2024).

  • High purity atropine solution for biochemical studies: The study developed a new method for solvent suppression in pure shift NMR, enhancing the understanding of atropine′s interactions at the molecular level, which is crucial for advancing analytical standards for delta8-THC and related compounds in scientific research (Gates et al., 2024).

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Marija Lukac et al.
European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie, 23(1), 80-84 (2013-02-05)
Evaluation of the effectiveness of oral atropine versus surgical therapy for hypertrophic pyloric stenosis (HPS). A total of 66 consecutive patients with HPS were treated at the University Children's Hospital between January 2006 and December 2011. The diagnosis was initially
Max J Hilz et al.
Stroke, 44(4), 1062-1069 (2013-02-21)
Pharmacological blockade showed sympathetic origin of 0.03 to 0.15 Hz blood pressure (BP) oscillations and parasympathetic origin of 0.15 to 0.5 Hz RR-interval (RRI) oscillations, but has not been used to determine origin of cerebral blood flow velocity (CBFV) oscillations
Yoshizumi Takemura et al.
American journal of physiology. Lung cellular and molecular physiology, 304(6), L428-L437 (2013-01-08)
We and others have shown that epithelial Na(+) channels (ENaC) in alveolar type 2 (AT2) cells are activated by β2 agonists, steroid hormones, elevated oxygen tension, and by dopamine. Although acetylcholine receptors (AChRs) have been previously described in the lung
Toshio Kitazawa
The Prostate, 73(9), 996-1006 (2013-02-08)
Prostate smooth muscle plays an important role in the physiological ejection of prostatic fluid and also in the pathogenesis of benign prostate hyperplasia. Although mouse is the best genetically engineered animal model to identify potential molecular targets for human diseases
Xian-Qiang Zhang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 37(21), 3223-3228 (2013-02-13)
To establish the hair roots culture system of Datura metel and study the hair roots growth and biosynthesis of scopolamine and hyoscyamine in hair roots culturing system. Direct degermed cotyledon of wild D. metel was infected by Agrobacterium tumefaciens strain

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