QBD10492

Aminooxy-dPEG^®₁₂-amido-dPEG^®₁₂-(m-dPEG^®₁₁)₃

• Empirical Formula (Hill Notation): C₁₃₆H₂₇₀N₆O₆₆
• Molecular Weight: 3045.60
• UNSPSC Code: 51171641
• PubChem Substance ID: 329823929
• NACRES: NA.22

Properties

• Assay: >90%
• form: solid or viscous liquid
• reaction suitability: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: carbonyl reactive
• polymer architecture: shape: branched; functionality: homofunctional
• shipped in: ambient
• storage temp.: −20°C
• SMILES string: O=C(NC(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)(COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)COCCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCOCCON)=O
• InChI key: XSNZUIBRYKKHCJ-UHFFFAOYSA-N

Description

Features and Benefits

Aminooxy-dPEG^®₁₂-amido-dPEG^®₁₂-(m-dPEG^®₁₁)₃ is a branched dPEG^® reagent that is highly useful for protein and peptide modification to increase hydrodynamic volume and serum half-life and to greatly reduce the immunogenicity of the modified peptide or protein. This dPEG^® product consists of a linear "tail" with a reactive group, a tris core to provide branching, and methoxy-terminated dPEG^® branches. The numbers following dPEG^® are the exact number of repeat units in the linear chain. This dPEG^® product is hydrophilic, non-immunogenic, single molecular weight compound. The aminooxy functional group reacts with aldehydes and ketones to form oxime bonds.

Legal Information

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable