M0505

Methylamine hydrochloride

≥98%

• Synonym(s): Methanaminium chloride, Methylamine monohydrochloride, Methylammonium chloride, Monomethylammonium chloride
• Linear Formula: CH₃NH₂ · HCl
• CAS Number: 593-51-1
• Molecular Weight: 67.52
• Beilstein: 3588822
• EC Number: 209-795-0
• MDL number: MFCD00012849
• UNSPSC Code: 12352100
• PubChem Substance ID: 57654342
• NACRES: NA.22

Properties

• Assay: ≥98%
• form: powder or crystals
• bp: 225-230 °C/15 mmHg (lit.)
• mp: 231-233 °C (lit.)
• solubility: H₂O: 1 g in 10 mL, clear, colorless
• SMILES string: Cl[H].CN
• InChI: 1S/CH5N.ClH/c1-2;/h2H2,1H3;1H
• InChI key: NQMRYBIKMRVZLB-UHFFFAOYSA-N

Description

General description

Methylamine hydrochloride is used as a buildingblock for the synthesis of various organic compounds.

Application

Methylamine hydrochloride can be used as a reactant to synthesize:

• Betahistine via aza-Michael reaction with 2-vinylpyridine in water.
• Azatripyrrolic and azatetrapyrrolic macrocycles by reacting with pyrrole and formaldehyde via base-catalyzed Mannich reaction.
• Tetrahydropyridines via Aza-Diels–Alder reaction with dienes and aldehydes.
• N-methylsecondary arylamines from aryl chlorides via nickel-catalyzed amination reaction.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 1
• Flash Point(F): 408.7 °F - closed cup
• Flash Point(C): 209.3 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves