Postgraduate medical journal, 67(783), 63-65 (1991-01-01)
Chronic lead poisoning has traditionally been treated by parenteral agents. We present a case where a comparison of ethylene diaminetetra-acetic acid was made with 2,3-dimethyl succinic acid (DMSA) which has the advantage of oral administration associated with little toxicity and
European journal of biochemistry, 121(2), 407-411 (1982-01-01)
Aldehyde reductase I from pig liver is strongly inhibited by cyclized NADP--2-oxodiacid adducts. This result, in conjunction with those showing a strong inhibitory effect of certain diacid derivatives, such as (+/-)-dimethylsuccinic acid, towards aldehyde reductase I, suggests the presence of
gem-Dimethylsuccinic acid and its higher homolog, 2-methyl-2-ethylsuccinic acid (MESA) are highly potent inhibitors of both carboxypeptidase A (CPA) and B. The inhibition constant of MESA for CPA (0.11 microM for the racemic mixture) is remarkable considering the relatively simple structure
Journal of the American Society of Nephrology : JASN, 13(11), 2628-2638 (2002-10-25)
The active transport of Krebs cycle intermediates, such as succinate, alpha-ketoglutarate, and citrate, is mediated by sodium-coupled transporters found in the luminal (NaDC-1) and basolateral plasma membranes (NaDC-3) of proximal tubule cells. This study used the two-electrode voltage clamp technique
Dalton transactions (Cambridge, England : 2003), 48(23), 8433-8441 (2019-05-23)
Six different chiral and achiral alkane dicarboxylic C4-acids, i.e. succinic acid (H2SUC), dl-2-methylsuccinic acid (H2MS), 2,3-dimethylsuccinic acid (H2DMS) and aspartic acid (d-, l- and dl-H2ASP), were used to obtain Ce(iv)-MOFs via microwave assisted reactions. In water-based syntheses, MOFs with three
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