The preparation and evaluation of novel aryl urea analogs as broad-spectrum antibacterial agents is described. Numerous compounds showed low micromolar minimum inhibitory concentrations (MIC) against both Gram-positive and Gram-negative bacteria. Selected analogs also exhibited in vivo efficacy in a lethal
Chemistry (Weinheim an der Bergstrasse, Germany), 19(12), 3842-3845 (2013-02-21)
Double-action haloketones: A super silyl group enabled the first highly diastereoselective Mukaiyama aldol reactions of α-chloro- and α-fluoroketones with a wide range of aldehydes, providing anti-β-siloxy-α-haloketones. This process is compatible with one-pot double-aldol methodology and allows for rapid access to
Synthesis, crystal structures, and antibacterial activity of a series of hydrazone compounds derived from 4-methylbenzohydrazide.
Lei Y, et al.
Journal of the Chilean Chemical Society, 60(2), 2961-2965 (2015)
Conformational Behavior of Conjugated Polymers With Oligo (phenylene vinylene) Side Chains.
Peeter H and Koeckelberghs G.
Macromolecular Chemistry and Physics, 214(5), 538-546 (2013)
Coordination-Driven Self-Assembly of Fullerene-Functionalized Pt (II) Metallacycles.
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