472654
N-Boc-2-aminoacetaldehyde
95%
Synonym(s):
tert-Butyl N-(2-oxoethyl)carbamate
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€72.40
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€229.00
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1 G
€72.40
5 G
€229.00
25 G
€685.00
About This Item
Linear Formula:
HCOCH2NHCO2C(CH3)3
CAS Number:
Molecular Weight:
159.18
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
95%
refractive index
n20/D 1.455 (lit.)
functional group
aldehyde
amine
storage temp.
−20°C
SMILES string
CC(C)(C)OC(=O)NCC=O
InChI
1S/C7H13NO3/c1-7(2,3)11-6(10)8-4-5-9/h5H,4H2,1-3H3,(H,8,10)
InChI key
ACNRTYKOPZDRCO-UHFFFAOYSA-N
Gene Information
human ... CTSK(1513)
General description
N-Boc-2-aminoacetaldehyde is an organic building block. It reacts with Horner-Wadsworth-Emmons (HWE) reagent to afford γ-aminobutyric acid (GABA)-derived α-keto amide/ester units.[1]
Application
α-Methylenation of this amino aldehyde proceeds in a quick and efficient manner using a recently reported protocol involving formaldehyde and catalysis by either pyrrolidine proprionic acid or the dipeptide L-Pro-β-Ala.[2]
Also used in a three-component synthesis of pyrrolidines involving 1,3-dipolar cycloaddition.[3]
Also used in a three-component synthesis of pyrrolidines involving 1,3-dipolar cycloaddition.[3]
N-Boc-2-aminoacetaldehyde may be employed in the following:
A building block in the synthesis of a protected pyrroloproline.[7]
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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