429120

3-Methoxybenzyl bromide

98%

• Synonym(s): 1-Bromomethyl-3-methoxybenzene
• Linear Formula: CH₃OC₆H₄CH₂Br
• CAS Number: 874-98-6
• Molecular Weight: 201.06
• MDL number: MFCD00216590
• UNSPSC Code: 12352100
• PubChem Substance ID: 24866839
• NACRES: NA.22

Properties

• Assay: 98%
• form: liquid
• refractive index: n20/D 1.575 (lit.)
• bp: 152 °C (lit.)
• density: 1.436 g/mL at 25 °C (lit.)
• SMILES string: COc1cccc(CBr)c1
• InChI: 1S/C8H9BrO/c1-10-8-4-2-3-7(5-8)6-9/h2-5H,6H2,1H3
• InChI key: ZKSOJQDNSNJIQW-UHFFFAOYSA-N

Description

General description

3-Methoxybenzyl bromide is a benzyl bromide derivative.

Application

3-Methoxybenzyl bromide (1-bromomethyl-3-methoxybenzene) may be used in the diastereoselective alkylation of vicinal dianions of chiral succinic acid derivatives.
It may be used in the synthesis of the following:

• 6-(3-methoxyphenyl)-hexane-2,4-dione
• N-(3-methoxybenzyl)-N-(1-methyl-1-phenylethyl)-amine
• 2-(3-methoxybenzyl)-3-[(1R)-7,7-dimethyl-2-oxobicyclo[2.2.1]hept-1-yl]-(3S)-2-thionia-bicyclo [2.2.1]- heptane tetrafluoroborate
• 1-(3-methoxybenzyl)-5-(1-methyl-1H-imidazol-5-yl)-1H-1,2,3-triazole

Safety Information

• Pictograms: GHS05
• Signal Word: Danger
• Hazard Statements: H314
• Precautionary Statements: P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 - P363 - P405
• Hazard Classifications: Eye Dam. 1 - Skin Corr. 1B
• Storage Class Code: 8A - Combustible corrosive hazardous materials
• WGK: WGK 3
• Flash Point(F): 235.4 °F - closed cup
• Flash Point(C): 113 °C - closed cup
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves