We report on a compact and cost-effective integrated label-free biosensor configuration which is based on the refractive index sensitivity of the localized surface plasmon resonance (LSPR) of gold nanostructures. Aiming for compactification and miniaturization of the sensor, arrays of nanodiscs
Focal adhesion kinase (FAK) is an important mediator of extracellular matrix-integrin mechano-signal transduction that regulates cell motility, survival, and proliferation. As such, FAK is being investigated as a potential therapeutic target for malignant and fibrotic diseases, and numerous clinical trials
3D inkjet printing is moving from a technology of rapid prototyping to rapid manufacturing. The introduction of ultraviolet curable composites filled with functional ceramics could expand the possibilities of this technology. In this work, a simple and scalable process was
Increased overall survival for patients with glioma brain tumours is associated with mutations in the metabolic regulator isocitrate dehydrogenase 1 (IDH1). Gliomas develop within a mechanically challenged microenvironment that is characterized by a dense extracellular matrix (ECM) that compromises vascular
Embryogenesis is directed by morphogens that induce differentiation within a defined tissue geometry. Tissue organization is mediated by cell-cell and cell-extracellular matrix (ECM) adhesions and is modulated by cell tension and tissue-level forces. Whether cell tension regulates development by modifying
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