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379506

Sigma-Aldrich

Tris(2,3-epoxypropyl) isocyanurate

Synonym(s):

1,3,5-Tris(oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione, TGIC, Triglycidyl isocyanurate

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100 G
€114.00
500 G
€433.00

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100 G
€114.00
500 G
€433.00

About This Item

Empirical Formula (Hill Notation):
C12H15N3O6
CAS Number:
2451-62-9
Molecular Weight:
297.26
EC Number:
219-514-3
MDL number:
MFCD00080670
UNSPSC Code:
12162002
PubChem Substance ID:
24863665
NACRES:
NA.23

€114.00

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form

powder

SMILES string

O=C1N(CC2CO2)C(=O)N(CC3CO3)C(=O)N1CC4CO4

InChI

1S/C12H15N3O6/c16-10-13(1-7-4-19-7)11(17)15(3-9-6-21-9)12(18)14(10)2-8-5-20-8/h7-9H,1-6H2

InChI key

OUPZKGBUJRBPGC-UHFFFAOYSA-N

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Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Muta. 1B - Skin Sens. 1 - STOT RE 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Listings

Regulatory Listings are mainly provided for chemical products. Only limited information can be provided here for non-chemical products. No entry means none of the components are listed. It is the user’s obligation to ensure the safe and legal use of the product.

EU REACH SVHC Candidate List

CAS No.

EU REACH Annex XVII (Restriction List)

CAS No.

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Certificates of Analysis (COA)

Lot/Batch Number
MKCQ9522
MKCS1814
MKCJ3740
MKBZ0640V
MKBW7248V

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Jing-Ping Wang et al.
Toxicology and applied pharmacology, 273(1), 110-120 (2013-08-21)
In this work, we demonstrated that the growth of human non-small-cell-lung-cancer cells H460 and A549 cells can be inhibited by low concentrations of an epoxide derivative, teroxirone, in both in vitro and in vivo models. The cytotoxicity was mediated by
G Atassi et al.
Cancer treatment reviews, 11 Suppl A, 99-110 (1984-03-01)
As a follow-up to our initial results on the antineoplastic activity of alpha-1,3,5-triglycidyl-s-triazinetrione (alpha TGT, NSC-296934, Teroxirone), many new epoxyde derivatives were tested against murine tumours, mostly against P388 leukaemia, to determine their antineoplastic role and to characterize their specific
P Dombernowsky et al.
Cancer chemotherapy and pharmacology, 11(1), 59-61 (1983-01-01)
alpha-1,3,5-Triglycidyl-s-triazinetrione (TGT) is a triepoxide derivative with alkylating properties discovered by random screening. TGT has been found to be active against a wide variety of murine tumors, including a P388 subline resistant to cyclophosphamide. The starting dose in this phase-I
Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint factory.
C S Munro et al.
Contact dermatitis, 26(1), 59-59 (1992-01-01)
Occupational contact dermatitis from triglycidyl isocyanurate in a powder paint sprayer.
J P McFadden et al.
Contact dermatitis, 28(4), 251-251 (1993-04-01)
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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