TPA-induced inhibition of gap junctional intercellular communication is not mediated through free radicals.: This research explores the role of N,N′-Diphenyl-p-phenylenediamine (DPPD) in cellular communication, providing insights into its applications in high-performance rubber stabilizers and life science manufacturing chemicals. (Hasler et al., 1990).
Journal of pharmacological sciences, 111(4), 433-439 (2009-12-08)
Cisplatin causes chronic interstitial disease with fibrosis, but the development mechanism of interstitial fibrosis is not yet understood. We examined the effect of an antioxidant, N,N'-diphenyl-1,4-phenylenediamine (DPPD), on development of interstitial fibrosis induced by cisplatin. Cisplatin increased blood urea nitrogen
This study was undertaken in order to examine the roles of lipid peroxidation and poly (ADP-ribose) polymerase (PARP) activation in oxidant-induced renal cell death. Opossum kidney cell cultures were used as the renal epithelial cell model, and an inorganic hydroperoxide
Although the tuberculin test has aided in the diagnosis of tuberculosis for more than 85 years, its interpretation is difficult particularly because sensitization with non-tuberculous mycobacteria leads to false positive tests. Using the guinea pig model of tuberculosis, we have
Molecular and biochemical parasitology, 118(1), 33-40 (2001-11-13)
It has been known for almost a century that normal human serum can lyse the extracellular blood parasite Trypanosoma brucei brucei. This process is a result of a non-immune killing factor in human sera known as trypanosome lytic factor (TLF).
The journal of physical chemistry. A, 113(16), 4780-4787 (2008-11-28)
Coarse-grained (CG) molecular dynamics (MD) simulations are performed to study the insertion of cyclic peptide nanotubes into cell membranes and to examine whether cyclic peptide nanotubes can function as an ion channel and thereby as an antibacterial agent. To do
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