- Conditional Deletion of
Conditional Deletion of
The Journal of neuroscience : the official journal of the Society for Neuroscience (2017-11-10)
Cleiton F Machado, Maíra H Nagai, Cassandra S Lyra, Thiago M Reis-Silva, André M Xavier, Isaias Glezer, Luciano F Felicio, Bettina Malnic
PMID29118104
ABSTRACT
The olfactory system can discriminate a vast number of odorants. This ability derives from the existence of a large family of odorant receptors expressed in the cilia of the olfactory sensory neurons. Odorant receptors signal through the olfactory-specific G-protein subunit, Gαolf. Ric-8b, a guanine nucleotide exchange factor, interacts with Gαolf and can amplify odorant receptor signal transduction
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