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  • Case report: severe symptomatic hyponatremia associated with lisinopril therapy.

Case report: severe symptomatic hyponatremia associated with lisinopril therapy.

The American journal of the medical sciences (1992-03-01)
D Subramanian, J C Ayus
ABSTRACT

A 63-year-old white female who was being treated for hypertension with lisinopril presented with seizures, altered mental status, and a serum sodium of 101 mEq/L. Serum sodium prior to initiation of lisinopril therapy was 137 mEq/L. The hyponatremia was corrected and did not recur after lisinopril was stopped. The hyponatremia may have been a result of polydipsia and inappropriate antidiuresis secondary to ACE-inhibitor therapy.

MATERIALS
Product Number
Brand
Product Description

Lisinopril dihydrate, European Pharmacopoeia (EP) Reference Standard
Supelco
Lisinopril, Pharmaceutical Secondary Standard; Certified Reference Material
Sigma-Aldrich
Lisinopril, ≥98% (HPLC)
USP
Lisinopril, United States Pharmacopeia (USP) Reference Standard