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Asterixis related to gabapentin intake: a case report and review.

Postgraduate medicine (2013-10-12)
Mervat Wahba, Olga Waln
ABSTRACT

Asterixis has been reported as a side effect of toxic and metabolic abnormalities. The current literature contains very little evidence of gabapentin-related neurotoxicity. Our observations reveal that neurotoxic side effects of gabapentin use may be seen even when dose adjustments are made for patients with mild-to-moderate renal dysfunction. Clinical vigilance for possible neurotoxic effects of gabapentin therapy in patients with renal dysfunction is warranted.

MATERIALS
Product Number
Brand
Product Description

Supelco
Gabapentin, Pharmaceutical Secondary Standard; Certified Reference Material
Supelco
Gabapentin solution, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®
Sigma-Aldrich
Gabapentin, solid
Supelco
Gabapentin Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material
USP
Gabapentin, United States Pharmacopeia (USP) Reference Standard