- [The pharmacological properties of coenzyme A disulfide].
[The pharmacological properties of coenzyme A disulfide].
Eksperimental'naia i klinicheskaia farmakologiia (1993-01-01)
V M Avakumov, Iu F Krylov, A L Karaev, A G Muliar, T N Smirnova, M A Kovler, E A Filina
PMID8324473
ABSTRACT
Coenzyme A disulfide (CoA disulfide) was pharmacologically studied. It has been found to normalize lipid and carbohydrate metabolism when given in a dose of 2 mg/kg, i.m., in diverse liver dysfunctions. It possesses an antihypoxic action under hemic and histotoxic hypoxia. When given in small doses (80-160 micrograms/kg, i.v.), CoA disulfide depresses the function of cellular hemostasis.
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