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[Hepatorenal syndrome: diagnosis, treatment and prevention].

Ugeskrift for laeger (2013-06-01)
Mads Egerod Israelsen, Lise Lotte Gluud, Flemming Bendtsen, Søren Møller, Aleksander Ahm Krag
ABSTRACT

Cirrhosis, ascites and renal impairment are associated with high morbidity and mortality. The hepatorenal syndrome (HRS) is a type of renal failure that affects patients with cirrhosis and ascites. This paper provides an update on evidence-based interventions in HRS. A number of factors can precipitate HRS. The monitoring, prevention, early detection, and correct treatment of these are essential. Terlipressin combined with albumin is the first-line treatment of type 1 HRS. In type 2 HRS with refractory ascites, liver transplantation and TIPS should be considered.