- Pd-catalyzed C-H fluorination with nucleophilic fluoride.
Pd-catalyzed C-H fluorination with nucleophilic fluoride.
Organic letters (2012-08-01)
Kate B McMurtrey, Joy M Racowski, Melanie S Sanford
PMID22844875
ABSTRACT
The palladium-catalyzed C-H fluorination of 8-methylquinoline derivatives with nucleophilic fluoride is reported. This transformation involves the use of AgF as the fluoride source in combination with a hypervalent iodine oxidant. Both the scope and mechanism of the reaction are discussed.
MATERIALS