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  • Synthesis of 2-Aryl benzothiazoles via K2S2O8-mediated oxidative condensation of benzothiazoles with aryl aldehydes.

Synthesis of 2-Aryl benzothiazoles via K2S2O8-mediated oxidative condensation of benzothiazoles with aryl aldehydes.

The Journal of organic chemistry (2012-07-28)
Zhiyong Yang, Xiang Chen, Sizhuo Wang, Jidan Liu, Kai Xie, Anwei Wang, Ze Tan
ABSTRACT

Nontransition metal-catalyzed synthesis of 2-aryl benzothiazoles was achieved through K(2)S(2)O(8)-mediated oxidative condensation of benzothiazoles with aryl aldehydes. The same transformation can also be effected when the aryl aldehydes were replaced with phenylglyoxylic acids.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Phenylglyoxylic acid, 97%
Sigma-Aldrich
Potassium peroxodisulfate, puriss. p.a., ACS reagent, ≥99.0% (RT)
Sigma-Aldrich
Phenylglyoxylic acid, purum, ≥98.0% (T)
Sigma-Aldrich
Potassium persulfate, 99.99% trace metals basis
Sigma-Aldrich
Potassium persulfate, ACS reagent, ≥99.0%