- One-pot cross-coupling of N-acyl N,O-acetals with alpha,beta-unsaturated compounds.
One-pot cross-coupling of N-acyl N,O-acetals with alpha,beta-unsaturated compounds.
Chemical communications (Cambridge, England) (2009-11-12)
Yong-Gang Xiang, Xiang-Wu Wang, Xiao Zheng, Yuan-Ping Ruan, Pei-Qiang Huang
PMID19904389
ABSTRACT
The synergistic action of BF(3).OEt(2) and SmI(2) allowed a series of intermolecular cross-couplings of readily available N-acyl N,O-acetals with alpha,beta-unsaturated compounds to be performed in high yields, which was applied to the stereoselective synthesis of pyrrolizidine alkaloid (+)-xenovenine.