- Highly enantioselective synthesis of isoxazoline N-oxides.
Highly enantioselective synthesis of isoxazoline N-oxides.
Chemical communications (Cambridge, England) (2008-05-16)
Chun-Yin Zhu, Xian-Ming Deng, Xiu-Li Sun, Jun-Cheng Zheng, Yong Tang
PMID18478708
ABSTRACT
The reaction of cinchonidine (cinchonine)-derived ammonium salts with nitroolefins in the presence of Cs2CO3 to afford optically active isoxazoline N-oxides with excellent ee and high de values has been developed.
MATERIALS