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G005170

SFC Analysis of Warfarin Enantiomers on Astec® Cellulose DMP, Methanol Additive

application for SFC

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About This Item

test parameters

column: Astec Cellulose DMP, 15 cm x 4.6 mm I.D., 5 μm particles (51098AST)
mobile phase: [A] CO2; [B] methanol; (80:20, A:B)
flow rate: 3 mL/min
pressure: 1450 psi (100 bar)
column temp.: 35 °C
detector: UV, 220 nm
injection: 5 μL
sample: warfarin enantiomers, 2 mg/mL

suitability

application for SFC

application(s)

clinical
pharmaceutical (small molecule)

Analysis Note

SFC data provided by Dr. Christina Kraml, Lotus Separations, LLC, Princeton, NJ.
Instrument: Berger Analytical SFCsystem equipped with a dual pump (FCM-1200), autosampler (ALS 3100), column oven (TCM-200) and diode-array detector (DAD-4100); from Mettler Toledo.

Legal Information

Astec is a registered trademark of Merck KGaA, Darmstadt, Germany

Analyte

Description
    Warfarin

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Chromatograms

application for HPLC

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