This product is soluble in water at approximately 2 mg/ml.
T5771
Testosterone 3-(O-carboxymethyl)oxime: BSA - fluorescein isothiocyanate conjugate
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5 MG
$496.00
About This Item
Recommended Products
assay
≥98.00% (TLC)
Quality Level
form
powder
drug control
regulated under CDSA - not available from Sigma-Aldrich Canada
extent of labeling
~3 mol FITC per mol BSA
~10 mol steroid per mol BSA
technique(s)
flow cytometry: suitable
solubility
water: 1.90-2.10 mg/mL, clear to faintly hazy, orange
shipped in
ambient
storage temp.
2-8°C
Application
Testosterone 3-(O-carboxymethyl)oxime: BSA-FITC has been used for flow cytometric assays in serum-free cell cultures2. It has also been used for fluorescence labeling experiments in L6 cells3.
Biochem/physiol Actions
Studies have reported that BSA-coupled testosterone can block the growth of LNCaP cells. Furthermore, it can activate Fas protein and cell death, as well as reduce the translocation, adhesion and incursion of iAR-negative, DU145 prostate cancer cells2.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Carc. 2
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type P3 (EN 143) respirator cartridges
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Nongenomic androgen actions imply mechanisms different from the classical intracellular androgen receptor (iAR) activation. We have recently reported the identification of a membrane androgen receptor (mAR) on LNCaP human prostate cancer cells, mediating testosterone signal transduction within minutes. In the
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How will you dissolve this product (T5771)?
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How can I dissolve the products that arrived in solid form?
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The spec sheet indicates that the product is tested for solubility at 2mg/ml in water. For Testosterone 3-(O-carboxymethyl)oxime: BSA, solubility is tested in Phosphate buffer pH 7.5. Additionally, without the albumin conjugate, Testosterone 3-(O-carboxymethyl)oxime is soluble in ethanol at 50mg/ml.
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