SRP6177

CETP human

recombinant, expressed in insect cells, ≥90% (SDS-PAGE)

• Synonym(s): BPIFF, Cholesteryl ester transfer protein, HDLCQ10, Lipid transfer protein I
• CAS Number: 1434215-51-6
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in insect cells
• assay: ≥90% (SDS-PAGE)
• form: lyophilized powder
• mol wt: 55 kDa
• packaging: pkg of 20 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: <1 EU/μg (LAL test)
• NCBI accession no.: P11597
• UniProt accession no.: Q8TCT0
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... CETP(1071)

Description

General description

Cholesteryl ester transfer protein (CETP), also called plasma lipid transfer protein, is a plasma protein that facilitates the transport of cholesteryl esters and triglycerides between the lipoproteins. It collects triglycerides from very-low-density (VLDL) or low-density lipoproteins (LDL) and exchanges them for cholesteryl esters from high-density lipoproteins (HDL), and vice versa. Inhibition of CETP has been proposed as a strategy to raise HDL cholesterol levels, a potential an approach to retarding atherogenesis and a strategy to reduce cardiovascular risk.

Physical form

Lyophilized from a Buffer containing 10 mM Tris and 150 mM NaCl.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile water at 2 mg/mL.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable