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SML3048

Tetrandrine

≥98% (HPLC)

Synonym(s):

(+)-Tetrandrine, (4aS,16aS)-3,4,4a,5,16a,17,18,19-Octahydro-12,21,22,26-tetramethoxy-4,17-dimethyl-16H-1,24:6,9-dietheno-11,15-metheno-2H-pyrido[2′,3′:17,18][1,11]dioxacycloeicosino[2,3,4-ij]isoquinoline, (S,S)-Tetrandrine, NSC 77037, Tetrandrin, (1β)-6,6′,7,12-Tetramethoxy-2,2′-dimethylberbaman

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Size/SKUAvailabilityPrice
10 mg

Available to ship TODAYfromMILWAUKEE

$90.70
50 mg

Available to ship TODAYfromMILWAUKEE

$368.00

About This Item

Empirical Formula (Hill Notation):
C38H42N2O6
CAS Number:
518-34-3
Molecular Weight:
622.75
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
MFCD08689909
Assay:
≥98% (HPLC)
Form:
powder

$90.70

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Quality Segment

100

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear

storage temp.

2-8°C

SMILES string

COc1ccc2C[C@@H]3N(C)CCc4cc(OC)c(OC)c(Oc5cc6[C@H](Cc7ccc(Oc1c2)cc7)N(C)CCc6cc5OC)c34

InChI

1S/C38H42N2O6/c1-39-15-13-25-20-32(42-4)34-22-28(25)29(39)17-23-7-10-27(11-8-23)45-33-19-24(9-12-31(33)41-3)18-30-36-26(14-16-40(30)2)21-35(43-5)37(44-6)38(36)46-34/h7-12,19-22,29-30H,13-18H2,1-6H3/t29-,30-/m0/s1

InChI key

WVTKBKWTSCPRNU-KYJUHHDHSA-N

Biochem/physiol Actions

Tetrandrine is bisbenzylisoquinoline alkaloid extracted from isolated from Stephania tetrandra S Moore that exhibits numerous pharmacological activities including anti-cancer, anti-inflammatory, negative ionotropic and chronotropic effects on myocardium, immunologic and antiallergenic effects. It has been used for treatment of tuberculosis, hyperglycemia, malaria, cancer and fever. Tetrandrine is potent calcium channel blocker. Tetrandrine targets multiple signaling pathways controlling cell cycle, apoptosis. Tetrandrine is an inhibitor of efflux pumps that reversed the clarithromycin resistance phenotype of some Mycobacterium avium complex clinical isolates.

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Tetrandrine ≥98% (HPLC)

Sigma-Aldrich

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Tetrandrine

Tetrandrine analytical standard, for drug analysis

Supelco

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Tetrandrine phyproof® Reference Substance

PHL89321

Tetrandrine

Cepharanthine ≥95% (HPLC)

Sigma-Aldrich

SML1269

Cepharanthine

description

≥98% (HPLC)

description

analytical standard, for drug analysis

description

phyproof® Reference Substance

description

≥95% (HPLC)

assay

≥98% (HPLC)

assay

≥90%

assay

≥95.0% (HPLC)

assay

≥95% (HPLC)

form

powder

form

solid

form

crystals

form

powder

Quality Level

100

Quality Level

100

Quality Level

-

Quality Level

100

storage temp.

2-8°C

storage temp.

-

storage temp.

−20°C

storage temp.

−20°C

solubility

DMSO: 2 mg/mL, clear

solubility

-

solubility

-

solubility

DMSO: 10 mg/mL, clear

color

white to beige

color

-

color

-

color

white to beige

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pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H300

Hazard Classifications

Acute Tox. 2 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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