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SML1305

Sigma-Aldrich

T56-LIMKi

≥98% (HPLC)

Synonym(s):

3-Methyl-N-[3-[[[3-(trifluoromethyl)phenyl]amino]carbonyl]phenyl]-5-isoxazolecarboxamide, T5601640

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About This Item

Empirical Formula (Hill Notation):
C19H14F3N3O3
CAS Number:
924473-59-6
Molecular Weight:
389.33
MDL number:
MFCD08495674
UNSPSC Code:
12352200
PubChem Substance ID:
329825772
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 20 mg/mL, clear

storage temp.

2-8°C

SMILES string

O=C(NC1=CC(C(F)(F)F)=CC=C1)C2=CC(NC(C3=CC(C)=NO3)=O)=CC=C2

InChI

1S/C19H14F3N3O3/c1-11-8-16(28-25-11)18(27)24-14-6-2-4-12(9-14)17(26)23-15-7-3-5-13(10-15)19(20,21)22/h2-10H,1H3,(H,23,26)(H,24,27)

InChI key

XVOKFRPKSAWELK-UHFFFAOYSA-N

Biochem/physiol Actions

T56-LIMKi is a LIMK2 inhibitor that reduces phosphorylated cofilin, and induces disassembly of actin stress fibers in NF1-/- MEFs cells.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H413

Hazard Classifications

Acute Tox. 3 Oral - Aquatic Chronic 4

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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