SML0983

5F-203

≥98% (HPLC)

• Synonym(s): 4-(5-Fluoro-2-benzothiazolyl)-2-methyl-benzenamine, 5F203, NSC-703786
• Empirical Formula (Hill Notation): C₁₄H₁₁FN₂S
• CAS Number: 260443-89-8
• Molecular Weight: 258.31
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Fc1cc2nc([s]c2cc1)c3cc(c(cc3)N)C
• InChI: 1S/C14H11FN2S/c1-8-6-9(2-4-11(8)16)14-17-12-7-10(15)3-5-13(12)18-14/h2-7H,16H2,1H3
• InChI key: IFWLHIIUGSEKKE-UHFFFAOYSA-N

Description

Biochem/physiol Actions

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death.

5F-203 is a cytotoxic molecule that forms DNA adducts that lead to cell death. 5F-203 induces aryl hydrocarbon receptor signaling, and elevates expression of CYP1A1. Treatment of cells with 5F-203 also leads to elevation of reactive oxygen species and activation of p38, JNK and ERK.

Features and Benefits

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Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable