SAE0219

Mucin Degradation Enzyme

for preparative digestions, powder

Properties

• Quality Level: 200
• form: powder
• shelf life: 2 yr (retest)
• storage condition: protect from light
• shipped in: dry ice
• storage temp.: -10 to -25°C

Description

General description

Mucin Degradation Enzyme is a metalloprotease useful for digesting heavily O-glycosylated mucin proteins. This product is made for preparative scale digestions of viscous material that is dense with mucin-type glycoproteins.

Application

For use as a sample preparation tool in research and discovery. Used for proteolytic degradation of mucin-dense tissues to allow for downstream processing.

Biochem/physiol Actions

The Mucin Degradation enzyme is a mutated form of a protease that specifically recognizes densely glycosylated mucins and mucin-domains, and proteolytically cleaves the peptide backbone. In nature this presumably enhances the virulence of the pathogenic microbe, but in the laboratory is a useful way of accessing molecular structures in tissues normally shielded by mucins.

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable