SAB5702306

Anti-HEC1/NDC80 Antibody, clone 4W2Y2, Rabbit Monoclonal

• Synonym(s): HEC, HEC1, HsHec1, KNTC2, TID3, hsNDC80
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 4W2Y2, monoclonal
• form: liquid
• mol wt: 76 kDa
• species reactivity: human
• concentration: 0.16 mg/mL
• technique(s): western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: ESTVNQGLSEAMNELDAVQREYQLVVQTTTEERRKVGNNLQRLLEMVATHVGSVEKHLEEQIAKVDREYEECMSEDLSENIKEIRDKYEKKATLIKSSEE
• UniProt accession no.: O14777
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... NDC80(10403)

Description

General description

This gene encodes a component of the NDC80 kinetochore complex. The encoded protein consists of an N-terminal microtubule binding domain and a C-terminal coiled-coiled domain that interacts with other components of the complex. This protein functions to organize and stabilize microtubule-kinetochore interactions and is required for proper chromosome segregation. [provided by RefSeq, Oct 2011]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 543-642 of human HEC1/NDC80 (O14777).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1