SAB5700435

Anti-Phospho-IRF3-S396 antibody produced in rabbit

• Synonym(s): IIAE7, IRF3
• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 12; 16; 33; 47; 49
• species reactivity: human, mouse, rat
• concentration: 0.69 mg/ml
• technique(s): western blot: 1:500-1:2000
• UniProt accession no.: Q14653
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer396)
• Gene Information: human ... IRF3(3661)

Description

General description

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Immunogen

A phospho specific peptide corresponding to residues surrounding S396 of human IRF3

Physical form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Storage and Stability

Store at -20℃. Avoid freeze / thaw cycles.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable