Cluster of differentiation 14 (CD14) is a cell surface glycoprotein expressed on monocytes and macrophages. It cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). It is also involved in NF-kappa-B activation, cytokine secretion, the inflammatory response, and up-regulation of cell surface molecules.
Immunogen
Synthetic peptide derived from the internal region of human CD14 protein.
Features and Benefits
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Physical form
0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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