SAB4300995

Anti-HSD17B13 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): HMFN0376, NIIL497, SCDR9, SDR16C3
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 34 kDa
• species reactivity: human
• concentration: 1.3 mg/mL
• technique(s): immunohistochemistry: 1:50- 1:200; western blot: 1:500-1:2000 (Cell Lysate)
• isotype: IgG
• accession no.: NP_001129702.1
• UniProt accession no.: Q7Z5P4
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... HSD17B13(345275)

Description

General description

Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is part of the short-chain dehydrogenase/reductase family. The gene encoding this lipid droplet-associated protein is localized on human chromosome 4q22.1.

Specificity

The antibody detects endogenous levels of total HSD17B13 protein.

Immunogen

Fusion protein corresponding to a region derived from internal residues of human hydroxysteroid (17-beta) dehydrogenase 13

Biochem/physiol Actions

Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) has a role in non-alcoholic fatty liver disease (NAFLD) and it has been shown to be downregulated in hepatocellular carcinoma. HSD17B13 modulates lipid biosynthesis.

Features and Benefits

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Physical form

Rabbit IgG in pH7.3 PBS, 0.05% NaN₃, 50% Glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1