SAB4300685

Anti-ASH2L antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-ASH2, Anti-ASH2L1, Anti-ASH2L2, Anti-Bre2
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: 65-80 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (G-R-R-S-P)
• NCBI accession no.: NM_004674.3
• UniProt accession no.: Q9UBL3
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... ASH2L(9070)

Description

General description

The antibody detects endogenous level of total ASH2L protein.

Immunogen

Peptide sequence around aa. 620-624 (G-R-R-S-P), according to the protein NP_004665.2

Features and Benefits

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Target description

Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates ′Lys-4′ of histone H3, but not if the neighboring ′Lys-9′ residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at ′Lys-4′ of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable