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P9192

Sigma-Aldrich

Pneumadin Rat

≥97% (HPLC)

Synonym(s):

Tyr-Gly-Glu-Pro-Lys-Leu-Asp-Ala-Gly-Val-NH2

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About This Item

Empirical Formula (Hill Notation):
C47H74N12O15
CAS Number:
130918-90-0
Molecular Weight:
1047.16
MDL number:
MFCD00214121
UNSPSC Code:
12352200

assay

≥97% (HPLC)

storage temp.

−20°C

SMILES string

CC(C)C[C@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(O)=O)NC(=O)CNC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](C(C)C)C(N)=O

Storage Class

13 - Non Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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J Kosowicz et al.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 36(2), 78-81 (2004-03-06)
Pneumadin (PNM) is a decapeptide originally isolated from mammalian lungs, and exerts a potent antidiuretic action by stimulating arginine-vasopressin release. We have recently developed a sensitive and specific radioimmunoassay (RIA) for rat PNM and detected high concentrations of PNM--not only
Jerzy Kosowicz et al.
Peptides, 24(2), 215-220 (2003-04-02)
Pneumadin (PNM) is a decapeptide, originally isolated from mammalian lungs, which exerts a potent stimulating effect on arginine-vasopressin (AVP) release, thereby evoking an antidiuretic effect. We have established a specific radioimmunoassay (RIA) method for rat PNM determination, the sensitivity of
Bogdan Miśkowiak et al.
Folia histochemica et cytobiologica, 41(4), 219-222 (2003-12-18)
Pneumadin (PNM) is a decapeptide (the rat peptide: Tyr-Gly-Glu-Pro-Lys-Leu-Asp-Ala-Gly-Val-NH2) isolated from mammalian lungs. Human and rat PNM differ only by substitution of one amino acid--Tyr/Ala. PNM evokes an antidiuretic effect via a potent stimulation of arginine-vasopressin (AVP) release. By means
A Markowska et al.
Histology and histopathology, 12(3), 677-682 (1997-07-01)
Pneumadin (PNM) is a biologically active decapeptide, which has previously been found to enhanced rat adrenal growth; the mechanism is indirect and probably involves the stimulation of both arginine-vasopressin (AVP) and ACTH release. The effects of 2- and 6-day PNM
J D Watson et al.
Regulatory peptides, 57(2), 105-114 (1995-05-30)
Pneumadin is an antidiuretic decapeptide, recently isolated from rat and human lung. Bolus intravenous injection of 5 nmol of pneumadin into water-loaded rats caused a rapid and significant antidiuresis and a reduction in Na+ and Cl- excretion. Pneumadin administration did
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