Skip to Content
MilliporeSigma
All Photos(1)

Key Documents

View All Documentation

M1818

Sigma-Aldrich

Molindone hydrochloride

≥98% (HPLC), solid

Synonym(s):

3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(4-morpholinylmethyl)-4H-indol-4-one hydrochloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C16H24N2O2 · HCl
CAS Number:
15622-65-8
Molecular Weight:
312.83
MDL number:
MFCD01718304
UNSPSC Code:
12352200
PubChem Substance ID:
24277995

Quality Level

100

assay

≥98% (HPLC)

form

solid

color

off-white

solubility

H2O: 19 mg/mL

originator

Endo

SMILES string

CCC1=C(C)NC2=C1C(C(CN3CCOCC3)CC2)=O.Cl

InChI

1S/C16H24N2O2.ClH/c1-3-13-11(2)17-14-5-4-12(16(19)15(13)14)10-18-6-8-20-9-7-18;/h12,17H,3-10H2,1-2H3;1H

InChI key

GQWNECFJGBQMBO-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813) , HTR2A(3356) , MAOA(4128) , MAOB(4129)

Looking for similar products? Visit Product Comparison Guide

Biochem/physiol Actions

D2 dopamine receptor antagonist; MAO inhibitor.

Features and Benefits

This compound was developed by Endo. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
014K4610V
014K4610

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Jennifer Dugan Stocks et al.
Journal of child and adolescent psychopharmacology, 22(2), 102-111 (2012-03-01)
To evaluate safety and tolerability of four doses of immediate-release molindone hydrochloride in children with attention-deficit/hyperactivity disorder (ADHD) and serious conduct problems. This open-label, parallel-group, dose-ranging, multicenter trial randomized children, aged 6-12 years, with ADHD and persistent, serious conduct problems
C Recasens
L'Encephale, 27(3), 269-276 (2001-08-08)
Weight gain associated with neuroleptics or antipsychotic treatment is well known by psychiatrists, but is too rarely considered as justifying a specific treatment program. Overweight is a risk factor for somatic disorders and can have a negative influence on self-esteem
T Baptista et al.
Pharmacopsychiatry, 35(6), 205-219 (2003-01-09)
Excessive body weight gain (BWG) is a common side effect of some typical and atypical antipsychotic drugs (APs). Convergent evidence suggests a hierarchy in the magnitude of BWG that may be induced by diverse agents, being very high for clozapine
Efficacy of molindone in treatment-refractory agitated schizophrenia: three case reports.
Michael Ciranni et al.
The Journal of clinical psychiatry, 69(6), 1018-1019 (2008-08-08)
Could repetitive transcranial magnetic stimulation improve neurocognition in early-onset schizophrenia spectrum disorders?
Paul E Croarkin et al.
Journal of the American Academy of Child and Adolescent Psychiatry, 51(9), 949-951 (2012-08-25)
View All Related Papers

Questions

Reviews

No rating value

Active Filters

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service