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L2136

Sigma-Aldrich

Lauric acid N,N-dimethylamide

~95%

Synonym(s):

N,N-Dimethyldodecanamide, N,N-Dimethyllauramide

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About This Item

Empirical Formula (Hill Notation):
C14H29NO
CAS Number:
Molecular Weight:
227.39
EC Number:
MDL number:
UNSPSC Code:
12352211
PubChem Substance ID:

assay

~95%

form

liquid

density

0.87 g/mL at 25 °C (lit.)

functional group

amide

shipped in

ambient

storage temp.

room temp

SMILES string

CCCCCCCCCCCC(=O)N(C)C

InChI

1S/C14H29NO/c1-4-5-6-7-8-9-10-11-12-13-14(16)15(2)3/h4-13H2,1-3H3

InChI key

BDYUSDIJIDGWCY-UHFFFAOYSA-N

Application

Dermal penetration enhancer; facilitates transport of solutes through the skin.

pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1 - Aquatic Chronic 1

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


Certificates of Analysis (COA)

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B B Michniak et al.
Journal of pharmaceutical sciences, 82(2), 214-219 (1993-02-01)
A series of novel dermal penetration enhancers, esters and amides of clofibric acid, was synthesized. The permeation parameters and skin retention of two steroids (hydrocortisone-21-acetate and betamethasone-17-valerate) in propylene glycol were studied with athymic nude mouse skin by in vitro
Kuo-Yen Huang et al.
EMBO molecular medicine, 13(1), e12828-e12828 (2020-11-08)
To circumvent the devastating pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, a humanized decoy antibody (ACE2-Fc fusion protein) was designed to target the interaction between viral spike protein and its cellular receptor, angiotensin-converting enzyme 2 (ACE2).

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