GE17-5317-02

Capto^™ MMC

Cytiva 17-5317-02, pack of 100 mL

• Synonym(s): Capto MMC Resin, MMC Chromatography Resin
• UNSPSC Code: 23151817
• NACRES: NA.56

Properties

• description: Ion Exchanger Type (value)
• packaging: pack of 100 mL
• manufacturer/tradename: Cytiva 17-5317-02
• matrix: highly cross-linked agarose
• avg. part. size: 75 μm (d50v)
• cleaning in place: 2-14
• working range: 2-12
• capacity: >45 mg binding capacity (BSA/ml medium at 30 mS/cm)
• suitability: suitable for bioprocess medium

Description

General description

Capto^™ MMC is a multimodal cation exchanger with a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges.

Capto^™ MMC is a multimodal cation exchanger, belonging to the Capto^™ family of BioProcess media for fast, efficient and cost-effective protein purification. Capto^™ MMC combines agarose base matrix developments with innovative ligand chemistry. It is composed of a rigid, high-flow agarose matrix and a novel multimodal ligand. The multimodal functionality gives Capto^™ MMC a different selectivity, compared with traditional ion exchangers. It can be used to bind proteins at the conductivity of the feed material and to solve specific purification challenges at both high and low ionic strengths.

The ligand contains caroxylic group and thus its features partly resemble a weak cation exchanger, but for Capto^™ MMC also several other types of interactions are involved, including hydrogen bonding and hydrophobic interactions.

Capto^™ MMC is available in a range of different bulk pack sizes and convenient pre-packed formats for easy scale-up and process development. As member of the BioProcess media range, Capto^™ MMC meets industrial demands with security of supply and comprehensive technical and regulatory support.

Dynamic binding capacity at 10% breakthrough as measured at a residence time of 2 min, 300 cm/h in a Tricorn 5/100 column with 10-cm bed height in 50 mM Sodium acetate, pH 4.75, 250 mM NaCl.

Features and Benefits

• Multimodal cation exchanger with a novel selectivity.
• High dynamic binding capacity at high conductivity increases productivity
• High-volume throughput cuts process times
• Smaller unit operations give cost-effective processing and reduce investments

Storage and Stability

Please be aware this product may be shipped 90 days before the expiration date. For more information on the batch specific expiration date, please contact technical service.

Store at 4 to 30 °C (20% Ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Legal Information

Capto is a trademark of Cytiva

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P280 - P210 - P241 - P235 - P303 + P361 + P353 - P501
• Storage Class: 3 - Flammable liquids